Everything else, e.g. Monday Musings, transfection trivia, announcements.
Earlier this year, Mirus Bio added RevIT™ AAV Enhancer to its established portfolio of reagents and kits for viral vector production to meet calls for more virus per transfection for any AAV construct.
Read on to learn how RevIT™ AAV Enhancer enables using less plasmid DNA to achieve high titers and percent full capsids!
Let’s ring in the new year with a list of all current FDA approved cell and gene therapies to date!
Read on to learn more about the 34 different treatments and cures.
“Shock me like an electric eel.” To creatures sharing an ecosystem in the Amazon, co-existing with electric eels and their jolting aura is a lifelong experience. A group of researchers from Nagoya University explored whether shocks from electric eels could mediate nucleic acid delivery to zebrafish larvae! Could these eels be the living embodiment of the Ingenio® EZporator® Electroporation System?
Special TransMission incoming!
Here we highlight some of the exciting results from Mirus’ ongoing collaboration with RoosterBio. Earlier this year, RoosterBio presented a poster at ASGCT and ISCT which showcased using TransIT-VirusGEN® for high-efficiency transfection of mRNA into human mesenchymal stromal cells (hMSCs) cultured in RoosterGEM™ medium. Both VirusGEN® and RoosterGEM™ have GMP formulations available, which allows for rapid implementation into clinical manufacturing processes that require highly qualified reagents.
Similarities between viral vectors and TransIT transfection reagents. Both are vehicles for gene delivery. Both can infiltrate cells. Read on for more Monday musings…
Have you ever given much thought to the relative size of the biological materials you work with every day in the lab? It can be mind-boggling to think about how something as tiny as a viral particle can have a life-saving impact for a patient with a debilitating genetic disease when delivered en masse.
But exactly how small of a package is all that life-changing power packed within? Test your knowledge in today’s blog post!
Special TransMission incoming from our GCC team leader (a.k.a. Director of Chemistry at Mirus Bio) Nick Rossi, Ph.D.!
In today’s TransMission, we bring you transfection trivia! Do you know when the word ‘transfection’ was coined?
Read on to learn about the evolution in meaning of the word ‘transfection.’
Where do you go to find awesome transfection reagents, dedicated process development support, and a lot of snow? Answer: Mirus Bio!
At Mirus Bio, headquartered in Madison, Wisconsin, USA, you can find a little snow in the winter and a dedicated team of Transfection Experts at the ready to fix all your transfection troubles, no matter how large or small.
In this post, we highlight a recent podcast with Bryan Piras (Director of Manufacturing) at St. Jude Children’s Research Hospital, where he describes how their Process Development team was able to overcome challenges encountered during scale-up from an adherent to a suspension cell AAV8 production platform.